Bone Marrow and Nonbone Marrow Toll Like Receptor 4 Regulate Acute Hepatic Injury Induced by Endotoxemia

BACKGROUND: Toll-like receptors (TLRs) are expressed in immune cells and hepatocytes. We examined whether hepatic Toll-like receptor 4 (TLR4) is involved in the acute hepatic injury caused by the administration of lipopolysaccharide (LPS) (septic shock model). METHODS: Wild type (WT), TLR4-deficient...

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Detalhes bibliográficos
Main Authors: Hochhauser, Edith, Avlas, Orna, Fallach, Reut, Bachmetov, Larissa, Zemel, Romy, Pappo, Orit, Shainberg, Asher, Ben Ari, Ziv
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744496/
https://ncbi.nlm.nih.gov/pubmed/23977376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073041
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