Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

Gastrointestinal nematode parasites infect over 1 billion humans, with little evidence for generation of sterilising immunity. These helminths are highly adapted to their mammalian host, following a developmental program through successive niches, while effectively down-modulating host immune respon...

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Detalhes bibliográficos
Main Authors: Hewitson, James P., Ivens, Al C., Harcus, Yvonne, Filbey, Kara J., McSorley, Henry J., Murray, Janice, Bridgett, Stephen, Ashford, David, Dowle, Adam A., Maizels, Rick M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744408/
https://ncbi.nlm.nih.gov/pubmed/23966853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003492
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