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Heligmosomoides polygyrus elicits a dominant non-protective antibody response directed against restricted glycan and peptide epitopes

Heligmosomoides polygyrus is a widely-used gastrointestinal helminth model of long-term chronic infection in mice, which has not been well-characterized at the antigenic level. We now identify the major targets of the murine primary antibody response as a subset of the secreted products in H. polygy...

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Publicat a:J Immunol
Autors principals: Hewitson, James P, Filbey, Kara J, Grainger, John R, Dowle, Adam A, Pearson, Mark, Murray, Janice, Harcus, Yvonne, Maizels, Rick M
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306209/
https://ncbi.nlm.nih.gov/pubmed/21964031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004140
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