PHD2 Silencing Enhances the Survival and Paracrine Function of Transplanted Adipose-Derived Stem Cells in Infarcted Myocardium

RATIONALE: Transplantation of stem cells into damaged hearts has had modest success as a treatment for ischemic heart disease. One of the limitations is the poor stem cell survival in the diseased microenvironment. Prolyl hydroxylase domain protein 2 (PHD2) is a cellular oxygen sensor that regulates...

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Detalhes bibliográficos
Main Authors: Wang, Wei Eric, Yang, Dezhong, Li, Liangpeng, Wang, Wei, Peng, Yulan, Chen, Caiyu, Chen, Peng, Xia, Xuewei, Wang, Hongyong, Jiang, Jiahui, Liao, Qiao, Li, Yuan, Xie, Ganfeng, Huang, Haiyun, Guo, Yanli, Ye, Linda, Duan, Dayue Darrel, Chen, Xiongwen, Houser, Steven R., Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744216/
https://ncbi.nlm.nih.gov/pubmed/23694817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.300929
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