Cost-effectiveness Analysis of UGT1A1 Genetic Testing to Inform Antiretroviral Prescribing in HIV Disease

BACKGROUND: Homozygosity for UGT1A1*28/*28 (Gilbert’s variant) has been reported to be associated with atazanavir-associated hyperbilirubinemia and premature atazanavir discontinuation. We assessed the potential cost-effectiveness of UGT1A1 testing to inform choice of an initial protease inhibitor-c...

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Detalhes bibliográficos
Main Authors: Schackman, Bruce R., Haas, David W., Becker, Jessica E., Berkowitz, Bethany K., Sax, Paul E., Daar, Eric S., Ribaudo, Heather J., Freedberg, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744167/
https://ncbi.nlm.nih.gov/pubmed/23264445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2500
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