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The Cost-Effectiveness of HLA-B*5701 Genetic Screening to Guide Initial Antiretroviral Therapy for HIV

OBJECTIVE: To evaluate the clinical impact and cost-effectiveness of HLA-B*5701 testing to guide selection of first-line HIV regimens in the United States. DESIGN: Cost-effectiveness analysis using a simulation model of HIV disease. The prevalence of HLA-B*5701 and the probabilities of confirmed and...

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Main Authors: Schackman, Bruce R., Scott, Callie A., Walensky, Rochelle P., Losina, Elena, Freedberg, Kenneth A., Sax, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648845/
https://ncbi.nlm.nih.gov/pubmed/18784465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283103ce6
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