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Alternative fates of newly formed PrP(Sc) upon prion conversion on the plasma membrane
Prion diseases are fatal neurodegenerative diseases characterised by the accumulation of misfolded prion protein (PrP(Sc)) in the brain. They are caused by the templated misfolding of normal cellular protein, PrP(C), by PrP(Sc). We have recently generated a unique cell system in which epitope-tagged...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744024/ https://ncbi.nlm.nih.gov/pubmed/23813960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.120477 |
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