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Using evolutionary computations to understand the design and evolution of gene and cell regulatory networks

This paper surveys modeling approaches for studying the evolution of gene regulatory networks (GRNs). Modeling of the design or ‘wiring’ of GRNs has become increasingly common in developmental and medical biology, as a means of quantifying gene-gene interactions, the response to perturbations, and t...

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Hlavní autoři: Spirov, Alexander, Holloway, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743956/
https://ncbi.nlm.nih.gov/pubmed/23726941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.05.013
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