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Using evolutionary computations to understand the design and evolution of gene and cell regulatory networks

This paper surveys modeling approaches for studying the evolution of gene regulatory networks (GRNs). Modeling of the design or ‘wiring’ of GRNs has become increasingly common in developmental and medical biology, as a means of quantifying gene-gene interactions, the response to perturbations, and t...

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Detalhes bibliográficos
Main Authors: Spirov, Alexander, Holloway, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743956/
https://ncbi.nlm.nih.gov/pubmed/23726941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.05.013
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