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Moving from Basic towards Systems Pharmacodynamic Models

Building upon many classical foundations of pharmacology, a diverse array of mechanistic pharmacokinetic-pharmacodynamic (PK/PD) models have emerged based on mechanisms of drug action and primary rate-limiting or turnover processes in physiology. An array of basic models can be extended to handle va...

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Bibliographic Details
Main Author: Jusko, William J
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743951/
https://ncbi.nlm.nih.gov/pubmed/23681608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23590
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