Natural Haemozoin Induces Expression and Release of Human Monocyte Tissue Inhibitor of Metalloproteinase-1

Recently matrix metalloproteinase-9 (MMP-9) and its endogenous inhibitor (tissue inhibitor of metalloproteinase-1, TIMP-1) have been implicated in complicated malaria. In vivo, mice with cerebral malaria (CM) display high levels of both MMP-9 and TIMP-1, and in human patients TIMP-1 serum levels dir...

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Bibliografiske detaljer
Main Authors: Polimeni, Manuela, Valente, Elena, Ulliers, Daniela, Opdenakker, Ghislain, Van den Steen, Philippe E., Giribaldi, Giuliana, Prato, Mauro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743797/
https://ncbi.nlm.nih.gov/pubmed/23967215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071468
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