Decoupling the Role of Ubiquitination for the Dislocation Versus Degradation of Major Histocompatibility Complex (MHC) Class I Proteins during Endoplasmic Reticulum-associated Degradation (ERAD)

Aberrantly or excessively expressed proteins in the endoplasmic reticulum are identified by quality control mechanisms and dislocated to the cytosol for proteasome-mediated, ubiquitin-dependent degradation by a process termed endoplasmic reticulum-associated degradation (ERAD). In addition to its ro...

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Hlavní autoři: Wang, Xiaoli, Yu, Y. Y. Lawrence, Myers, Nancy, Hansen, Ted H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Protein Synthesis and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743500/
https://ncbi.nlm.nih.gov/pubmed/23801327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482018
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