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Identification of PDCL3 as a Novel Chaperone Protein Involved in the Generation of Functional VEGF Receptor 2

Angiogenesis, a hallmark step in tumor metastasis and ocular neovascularization, is driven primarily by the function of VEGF ligand on one of its receptors, VEGF receptor 2 (VEGFR-2). Central to the proliferation and ensuing angiogenesis of endothelial cells, the abundance of VEGFR-2 on the surface...

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Detalhes bibliográficos
Main Authors: Srinivasan, Srimathi, Meyer, Rosana D., Lugo, Ricardo, Rahimi, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743489/
https://ncbi.nlm.nih.gov/pubmed/23792958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473173
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