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Mechanism of differentiation-enhanced photodynamic therapy of cancer: Upregulation of coproporphyrinogen oxidase by C/EBP transcription factors
The efficacy of Photodynamic therapy (PDT) for epithelial cancers is increased when PDT is combined with calcitriol (Vit D), a form of Differentiation therapy (DT). Here we describe an underlying mechanism for this effect. Differentiation-promoting agents are known to upregulate CCAAT-enhancer bindi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743443/ https://ncbi.nlm.nih.gov/pubmed/23686770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0047 |
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