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Mechanism of differentiation-enhanced photodynamic therapy of cancer: Upregulation of coproporphyrinogen oxidase by C/EBP transcription factors

The efficacy of Photodynamic therapy (PDT) for epithelial cancers is increased when PDT is combined with calcitriol (Vit D), a form of Differentiation therapy (DT). Here we describe an underlying mechanism for this effect. Differentiation-promoting agents are known to upregulate CCAAT-enhancer bindi...

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Detalhes bibliográficos
Main Authors: Anand, Sanjay, Hasan, Tayyaba, Maytin, Edward V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743443/
https://ncbi.nlm.nih.gov/pubmed/23686770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0047
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