Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes

Molecular mechanisms of leukemogenesis have been successfully unraveled by studying genes involved in simple rearrangements including balanced translocations and inversions. In contrast, little is known about genes altered in complex karyotypic abnormalities. We studied acute myeloid leukemia (AML)...

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Detalhes bibliográficos
Main Authors: Baldus, Claudia D., Liyanarachchi, Sandya, Mrózek, Krzysztof, Auer, Herbert, Tanner, Stephan M., Guimond, Martin, Ruppert, Amy S., Mohamed, Nehad, Davuluri, Ramana V., Caligiuri, Michael A., Bloomfield, Clara D., de la Chapelle, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374344/
https://ncbi.nlm.nih.gov/pubmed/15007164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400272101
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