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Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease
Whereas many cases of neurodegenerative disease feature the abnormal accumulation of protein, an abundance of recent literature highlights loss of RNA homeostasis as a ubiquitous and central feature of pathological states. In some diseases expanded repeats have been identified in non-coding regions...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743304/ https://ncbi.nlm.nih.gov/pubmed/23967011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00149 |
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