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Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease

Whereas many cases of neurodegenerative disease feature the abnormal accumulation of protein, an abundance of recent literature highlights loss of RNA homeostasis as a ubiquitous and central feature of pathological states. In some diseases expanded repeats have been identified in non-coding regions...

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Autori principali: Gray, Douglas A., Woulfe, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743304/
https://ncbi.nlm.nih.gov/pubmed/23967011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00149
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