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Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell of origin model for prostate cancer heterogeneity

A key issue in cancer biology is whether oncogenic transformation of different cell types of origin within an adult tissue gives rise to distinct tumor subtypes that differ in their prognosis and/or treatment response. We now show that initiation of prostate tumors in basal or luminal epithelial cel...

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書誌詳細
主要な著者: Wang, Zhu A., Mitrofanova, Antonina, Bergren, Sarah K., Abate-Shen, Cory, Cardiff, Robert D., Califano, Andrea, Shen, Michael M.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743266/
https://ncbi.nlm.nih.gov/pubmed/23434823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2697
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