Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling

Heparan sulfate (HS), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. HSPGs modulate functions of several growth factors and signaling molecules. We examined whether small intestinal epithelial HS plays some roles in crypt homeostasis using intestin...

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Hlavní autoři: Yamamoto, Shuji, Nakase, Hiroshi, Matsuura, Minoru, Honzawa, Yusuke, Matsumura, Kayoko, Uza, Norimitsu, Yamaguchi, Yu, Mizoguchi, Emiko, Chiba, Tsutomu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Hormones and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742857/
https://ncbi.nlm.nih.gov/pubmed/23744737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00480.2012
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