Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling

Heparan sulfate (HS), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. HSPGs modulate functions of several growth factors and signaling molecules. We examined whether small intestinal epithelial HS plays some roles in crypt homeostasis using intestin...

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Detalhes bibliográficos
Main Authors: Yamamoto, Shuji, Nakase, Hiroshi, Matsuura, Minoru, Honzawa, Yusuke, Matsumura, Kayoko, Uza, Norimitsu, Yamaguchi, Yu, Mizoguchi, Emiko, Chiba, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742857/
https://ncbi.nlm.nih.gov/pubmed/23744737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00480.2012
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