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Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108

Pancreatic carcinoma is one of the cancers with the worse prognosis, thus any therapeutic improvement is imperative. Cytotoxic LH-RH analog, AN-152 (proprietary designation, AEZS-108), consisting of doxorubicin (DOX) conjugated to D-Lys(6)LH-RH, is now in clinical trials for targeted therapy of seve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Szepeshazi, Karoly, Schally, Andrew V., Block, Norman L., Halmos, Gabor, Nadji, Mehrdad, Szalontay, Luca, Vidaurre, Irving, Abi-Chaker, Andrew, Rick, Ferenc G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742835/
https://ncbi.nlm.nih.gov/pubmed/23744510
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