Induction of Autoantibodies to CCR5 in Macaques and Subsequent Effects upon Challenge with an R5-Tropic Simian/Human Immunodeficiency Virus

Antibodies against CCR5, the major coreceptor for human immunodeficiency virus type 1 (HIV-1), may have antiviral potential as viral fusion inhibitors. In this study, we generated a virus-like particle (VLP)-based vaccine that effectively breaks B-cell tolerance and elicits autoantibodies against CC...

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Bibliographische Detailangaben
Hauptverfasser: Chackerian, Bryce, Briglio, Lindsey, Albert, Paul S., Lowy, Douglas R., Schiller, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC374281/
https://ncbi.nlm.nih.gov/pubmed/15047820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.8.4037-4047.2004
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