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n→π* Interactions of Amides and Thioamides: Implications for Protein Stability

[Image: see text] Carbonyl–carbonyl interactions between adjacent backbone amides have been implicated in the conformational stability of proteins. By combining experimental and computational approaches, we show that relevant amidic carbonyl groups associate through an n→π* donor–acceptor interactio...

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Detalhes bibliográficos
Main Authors: Newberry, Robert W., VanVeller, Brett, Guzei, Ilia A., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742804/
https://ncbi.nlm.nih.gov/pubmed/23663100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4033583
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