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n→π* Interactions of Amides and Thioamides: Implications for Protein Stability

[Image: see text] Carbonyl–carbonyl interactions between adjacent backbone amides have been implicated in the conformational stability of proteins. By combining experimental and computational approaches, we show that relevant amidic carbonyl groups associate through an n→π* donor–acceptor interactio...

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Библиографические подробности
Главные авторы: Newberry, Robert W., VanVeller, Brett, Guzei, Ilia A., Raines, Ronald T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2013
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742804/
https://ncbi.nlm.nih.gov/pubmed/23663100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4033583
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