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n→π* Interactions of Amides and Thioamides: Implications for Protein Stability

[Image: see text] Carbonyl–carbonyl interactions between adjacent backbone amides have been implicated in the conformational stability of proteins. By combining experimental and computational approaches, we show that relevant amidic carbonyl groups associate through an n→π* donor–acceptor interactio...

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Détails bibliographiques
Auteurs principaux: Newberry, Robert W., VanVeller, Brett, Guzei, Ilia A., Raines, Ronald T.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2013
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742804/
https://ncbi.nlm.nih.gov/pubmed/23663100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4033583
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