Загрузка...

Targeted Exon Sequencing Successfully Discovers Rare Causative Genes and Clarifies the Molecular Epidemiology of Japanese Deafness Patients

Target exon resequencing using Massively Parallel DNA Sequencing (MPS) is a new powerful strategy to discover causative genes in rare Mendelian disorders such as deafness. We attempted to identify genomic variations responsible for deafness by massive sequencing of the exons of 112 target candidate...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Miyagawa, Maiko, Naito, Takehiko, Nishio, Shin-ya, Kamatani, Naoyuki, Usami, Shin-ichi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742761/
https://ncbi.nlm.nih.gov/pubmed/23967202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071381
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!