Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Lung Cancer Patients

Histone deacetylase inhibitor (HDACi, vorinostat) responses were studied in murine and human lung cancer cell lines and genetically-engineered mouse lung cancer models. Findings were compared with a window of opportunity trial in aerodigestive tract cancers. In human (HOP62, H522 and H23) and murine...

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Main Authors: Ma, Tian, Galimberti, Fabrizio, Erkmen, Cherie P., Memoli, Vincent, Chinyengetere, Fadzai, Sempere, Lorenzo, Beumer, Jan H., Anyang, Bean N., Nugent, William, Johnstone, David, Tsongalis, Gregory J., Kurie, Jonathan M., Li, Hua, DiRenzo, James, Guo, Yongli, Freemantle, Sarah J., Dragnev, Konstantin H., Dmitrovsky, Ethan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742691/
https://ncbi.nlm.nih.gov/pubmed/23686769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0933
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