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Intraventricular Hemorrhage Induces Deposition of Proteoglycans in Premature Rabbits, but Their In Vivo Degradation with Chondroitinase Does Not Restore Myelination, Ventricle Size and Neurological Recovery

Intraventricular hemorrhage (IVH) results in white matter injury and hydrocephalus in premature infants. Chondroitin sulfate proteoglycans (CSPGs)--neuorcan, brevican, versican, aggrecan and phosphacan—are unregulated in the extracellular matrix after brain injury, and their degradation enhances pla...

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Autors principals: Vinukonda, Govindaiah, Zia, Muhammad T., Bhimavarapu, Bala B. R., Hu, Furong, Feinberg, Michelle, Bokhari, Aquiba, Ungvari, Zoltan, Fried, Victor A., Ballabh, Praveen
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742687/
https://ncbi.nlm.nih.gov/pubmed/23474192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.02.018
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