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Intraventricular Hemorrhage Induces Deposition of Proteoglycans in Premature Rabbits, but Their In Vivo Degradation with Chondroitinase Does Not Restore Myelination, Ventricle Size and Neurological Recovery

Intraventricular hemorrhage (IVH) results in white matter injury and hydrocephalus in premature infants. Chondroitin sulfate proteoglycans (CSPGs)--neuorcan, brevican, versican, aggrecan and phosphacan—are unregulated in the extracellular matrix after brain injury, and their degradation enhances pla...

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Detalhes bibliográficos
Main Authors: Vinukonda, Govindaiah, Zia, Muhammad T., Bhimavarapu, Bala B. R., Hu, Furong, Feinberg, Michelle, Bokhari, Aquiba, Ungvari, Zoltan, Fried, Victor A., Ballabh, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742687/
https://ncbi.nlm.nih.gov/pubmed/23474192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.02.018
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