Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Envelope Glycoprotein gB Induces the Integrin-Dependent Focal Adhesion Kinase-Src-Phosphatidylinositol 3-Kinase-Rho GTPase Signal Pathways and Cytoskeletal Rearrangements

Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) envelope glycoprotein gB possesses an RGD motif, interacts with α3β1 integrin, and uses it as one of the entry receptors. HHV-8 induces the integrin-dependent focal adhesion kinase (FAK), a critical step in the outside-in sign...

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Detalhes bibliográficos
Main Authors: Sharma-Walia, Neelam, Naranatt, Pramod P., Krishnan, Harinivas H., Zeng, Ling, Chandran, Bala
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374261/
https://ncbi.nlm.nih.gov/pubmed/15047836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.8.4207-4223.2004
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