Kaposi's Sarcoma-Associated Herpesvirus Induces the Phosphatidylinositol 3-Kinase-PKC-ζ-MEK-ERK Signaling Pathway in Target Cells Early during Infection: Implications for Infectivity

Human herpesvirus 8 (HHV-8) is implicated in the pathogenesis of Kaposi's sarcoma. HHV-8 envelope glycoprotein B (gB) possesses the RGD motif known to interact with integrin molecules, and HHV-8 infectivity was inhibited by RGD peptides, by antibodies against α3 and β1 integrins, and by soluble α3β1...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Naranatt, Pramod P., Akula, Shaw M., Zien, Christopher A., Krishnan, Harinivas H., Chandran, Bala
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502866/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.1524-1539.2003
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