Preventive Effect of Dipeptidyl Peptidase-4 Inhibitor on Atherosclerosis Is Mainly Attributable to Incretin's Actions in Nondiabetic and Diabetic Apolipoprotein E-Null Mice

AIM: Several recent reports have revealed that dipeptidyl peptidase (DPP)-4 inhibitors have suppressive effects on atherosclerosis in apolipoprotein E-null (Apoe (−/−)) mice. It remains to be seen, however, whether this effect stems from increased levels of the two active incretins, glucagon-like pe...

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Autors principals: Terasaki, Michishige, Nagashima, Masaharu, Nohtomi, Kyoko, Kohashi, Kyoko, Tomoyasu, Masako, Sinmura, Kyoko, Nogi, Yukinori, Katayama, Yuki, Sato, Kengo, Itoh, Fumiko, Watanabe, Takuya, Hirano, Tsutomu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742603/
https://ncbi.nlm.nih.gov/pubmed/23967137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070933
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