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GLIOMAS PROMOTE IMMUNOSUPPRESSION THROUGH INDUCTION OF B7-H1 EXPRESSION IN TUMOR-ASSOCIATED MACROPHAGES
PURPOSE: Gliomas are known to induce local and systemic immunosuppression, inhibiting T cell-mediated cytotoxic responses to tumor growth. Tumor-associated macrophages are a significant component of the immune infiltrate in gliomas and may express immunosuppressive surface ligands, such as B7-H1. EX...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742575/ https://ncbi.nlm.nih.gov/pubmed/23613317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3314 |
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