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Exposure to estrogen and ionizing radiation causes epigenetic dysregulation, activation of mitogen-activated protein kinase pathways, and genome instability in the mammary gland of ACI rats

The impact of environmental mutagens and carcinogens on the mammary gland has recently received a lot of attention. Among the most generally accepted carcinogenic agents identified as factors that may increase breast cancer incidence are ionizing radiation and elevated estrogen levels. However, the...

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Main Authors: Kutanzi, Kristy, Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742486/
https://ncbi.nlm.nih.gov/pubmed/23792640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.24599
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