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Mobilization of LINE-1 in irradiated mammary gland tissue may potentially contribute to low dose radiation-induced genomic instability

It is known that cellular stresses such as ionizing radiation activate LINE-1 (long interspersed nuclear element type 1, L1), but the molecular mechanisms of LINE-1 activation have not been fully elucidated. There is a possibility that DNA methylation changes induced by genotoxic stresses might cont...

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Bibliografische gegevens
Gepubliceerd in:Genes Cancer
Hoofdauteurs: Luzhna, Lidia, Ilnytskyy, Yaroslav, Kovalchuk, Olga
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362486/
https://ncbi.nlm.nih.gov/pubmed/25821563
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