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Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase

The vestibular system of the inner ear is responsible for the perception of motion and gravity. Key elements of this organ are otoconia, tiny biomineral particles in the utricle and the saccule. In response to gravity or linear acceleration, otoconia deflect the stereocilia of the hair cells, thus t...

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Hlavní autoři: Paffenholz, Rainer, Bergstrom, Rebecca A., Pasutto, Francesca, Wabnitz, Philipp, Munroe, Robert J., Jagla, Wolfgang, Heinzmann, Ulrich, Marquardt, Andreas, Bareiss, Armin, Laufs, Jürgen, Russ, Andreas, Stumm, Gabriele, Schimenti, John C., Bergstrom, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC374230/
https://ncbi.nlm.nih.gov/pubmed/15014044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1172504
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