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Proteolytic Cleavage of Apolipoprotein E4 as the Keystone for the Heightened Risk Associated with Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by microscopic lesions consisting of beta-amyloid plaques and neurofibrillary tangles (NFTs). The majority of cases are defined as sporadic and are likely caused by a combination of both genetic and environmental facto...

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Detalles Bibliográficos
Autor principal: Rohn, Troy T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742279/
https://ncbi.nlm.nih.gov/pubmed/23867607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140714908
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