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miR-29 Represses the Activities of DNA Methyltransferases and DNA Demethylases

Members of the microRNA-29 (miR-29) family directly target the DNA methyltransferases, DNMT3A and DNMT3B. Disturbances in the expression levels of miR-29 have been linked to tumorigenesis and tumor aggressiveness. Members of the miR-29 family are currently thought to repress DNA methylation and supp...

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Detalhes bibliográficos
Main Authors: Morita, Sumiyo, Horii, Takuro, Kimura, Mika, Ochiya, Takahiro, Tajima, Shoji, Hatada, Izuho
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742264/
https://ncbi.nlm.nih.gov/pubmed/23857059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140714647
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