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A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium

Ocular gene therapy has been extensively explored in recent years as a therapeutic avenue to target diseases of the cornea, retina and retinal pigment epithelium (RPE). Adeno-associated virus (AAV)-mediated gene therapy has shown promise in several RPE clinical trials but AAVs have limited payload c...

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Bibliografiska uppgifter
Huvudupphovsmän: Koirala, Adarsha, Conley, Shannon M., Naash, Muna I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742069/
https://ncbi.nlm.nih.gov/pubmed/23796578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.06.002
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