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A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium
Ocular gene therapy has been extensively explored in recent years as a therapeutic avenue to target diseases of the cornea, retina and retinal pigment epithelium (RPE). Adeno-associated virus (AAV)-mediated gene therapy has shown promise in several RPE clinical trials but AAVs have limited payload c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742069/ https://ncbi.nlm.nih.gov/pubmed/23796578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.06.002 |
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