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Nanoparticle-mediated gene transfer specific to retinal pigment epithelial cells

Previously, we demonstrated that CK30PEG10k-compacted DNA nanoparticles (NPs) efficiently target photoreceptor cells and improve visual function in a retinitis pigmentosa model. Here, we test the ability of these NPs in driving transgene expression in the retinal pigment epithelium (RPE), using an R...

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Autors principals: Koirala, Adarsha, Makkia, Rasha S., Cooper, Mark J., Naash, Muna I.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321842/
https://ncbi.nlm.nih.gov/pubmed/21885113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.08.062
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