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Connecting the genome: dynamics and stochasticity in a new hierarchy for chromosome conformation

Mammalian genomes encode genetic information in their linear sequence, but appropriate expression of their genes requires chromosomes to fold into complex three-dimensional structures. Transcriptional control involves the establishment of physical connections among genes and regulatory elements, bot...

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Bibliographic Details
Main Authors: Gibcus, Johan H., Dekker, Job
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741673/
https://ncbi.nlm.nih.gov/pubmed/23473598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.011
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