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SOD2 deficiency in hematopoietic cells in mice results in reduced red blood cell deformability and increased heme degradation
Among the three types of super oxide dismutases (SODs) known, SOD2 deficiency is lethal in neonatal mice owing to cardiomyopathy caused by severe oxidative damage. SOD2 is found in red blood cell (RBC) precursors, but not in mature RBCs. To investigate the potential damage to mature RBCs resulting f...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741644/ https://ncbi.nlm.nih.gov/pubmed/23142655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2012.10.017 |
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