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Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma

Dedicator of cytokinesis 3 (Dock3), a new member of the guanine nucleotide exchange factors for the small GTPase Rac1, promotes axon regeneration following optic nerve injury. In the present study, we found that Dock3 directly binds to the intracellular C-terminus domain of NR2B, an N-methyl- -aspar...

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Main Authors: Namekata, K, Kimura, A, Kawamura, K, Guo, X, Harada, C, Tanaka, K, Harada, T
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741514/
https://ncbi.nlm.nih.gov/pubmed/23852370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.91
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