Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids

The phagocytic clearance of apoptotic cells is essential to prevent chronic inflammation and autoimmunity. The phosphatidylserine-binding protein milk fat globule-EGF factor 8 (MFG-E8) is a major opsonin for apoptotic cells, and MFG-E8(−/−) mice spontaneously develop a lupus-like disease. Similar to...

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Autors principals: Lauber, K, Keppeler, H, Munoz, L E, Koppe, U, Schröder, K, Yamaguchi, H, Krönke, G, Uderhardt, S, Wesselborg, S, Belka, C, Nagata, S, Herrmann, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741508/
https://ncbi.nlm.nih.gov/pubmed/23832117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.82
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