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Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids
The phagocytic clearance of apoptotic cells is essential to prevent chronic inflammation and autoimmunity. The phosphatidylserine-binding protein milk fat globule-EGF factor 8 (MFG-E8) is a major opsonin for apoptotic cells, and MFG-E8(−/−) mice spontaneously develop a lupus-like disease. Similar to...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741508/ https://ncbi.nlm.nih.gov/pubmed/23832117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.82 |
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