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Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice

Despite being the most evolutionarily conserved of the mammalian caspases, little is understood about the cellular function of caspase-2 in normal tissues or what role caspase-2 may have in the progression of human disease. It has been reported that deletion of the caspase-2 gene (Casp2), accelerate...

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Detalhes bibliográficos
Main Authors: Parsons, M J, McCormick, L, Janke, L, Howard, A, Bouchier-Hayes, L, Green, D R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741497/
https://ncbi.nlm.nih.gov/pubmed/23645210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.38
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