Radicicol Inhibits iNOS Expression in Cytokine-Stimulated Pancreatic Beta Cells

Here, we show that radicicol, a fungal antibiotic, resulted in marked inhibition of inducible nitric oxide synthase (iNOS) transcription by the pancreatic beta cell line MIN6N8a in response to cytokine mixture (CM: TNF-α, IFN-γ, and IL-1β). Treatment of MIN6N8a cells with radicicol inhibited CM-stim...

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Detalhes bibliográficos
Main Authors: Youn, Cha Kyung, Park, Seon Joo, Li, Mei Hong, Lee, Min Young, Lee, Kun Yeong, Cha, Man Jin, Kim, Ok Hyeun, You, Ho Jin, Chang, In Youp, Yoon, Sang Pil, Jeon, Young Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741488/
https://ncbi.nlm.nih.gov/pubmed/23946691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2013.17.4.315
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