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Mycobacterium tuberculosis PE_PGRS17 Promotes the Death of Host Cell and Cytokines Secretion via Erk Kinase Accompanying with Enhanced Survival of Recombinant Mycobacterium smegmatis

Tuberculosis (TB) remains a serious threat to global public health, largely due to the successful manipulation of the host immunity by its etiological agent Mycobacterium tuberculosis. The PE_PGRS protein family of M. tuberculosis might be a contributing factor. To investigate the roles of PE_PGRS17...

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Detalhes bibliográficos
Main Authors: Chen, Tian, Zhao, Quanju, Li, Wu, Xie, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741429/
https://ncbi.nlm.nih.gov/pubmed/23663047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0083
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