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Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

Suppression of major histocompatibility complex (MHC) class II antigen presentation is believed to be among the major mechanisms used by Mycobacterium tuberculosis to escape protective host immune responses. Through a genome-wide screen for the genetic loci of M. tuberculosis that inhibit MHC class...

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Publicado en:Nat Microbiol
Autores principales: Saini, Neeraj K., Baena, Andres, Ng, Tony W., Venkataswamy, Manjunatha M., Kennedy, Steven C., Kunnath-Velayudhan, Shajo, Carreño, Leandro J., Xu, Jiayong, Chan, John, Larsen, Michelle H., Jacobs, William R., Porcelli, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662936/
https://ncbi.nlm.nih.gov/pubmed/27562263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.133
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