Chaperone Activity of α B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis

For 15 y, α B-crystallin (heat shock protein [Hsp[ B5) has been labeled an autoantigen in multiple sclerosis (MS) based on humoral and cellular responses found in humans and animal models. However, there have been several scientific inconsistencies with this assignment, ranging from studies demonstr...

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Detalhes bibliográficos
Main Authors: Rothbard, Jonathan B., Zhao, Xiaoyan, Sharpe, Orr, Strohman, Michael J., Kurnellas, Michael, Mellins, Elizabeth D., Robinson, William H., Steinman, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741407/
https://ncbi.nlm.nih.gov/pubmed/21357544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003934
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