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Impaired insulin-mediated vasorelaxation in a non-obese model of type 2 diabetes: Role of endothelin-1
Insulin resistance involves decreased phosphorylation of insulin receptor substrate (IRS) proteins and/or Akt. In the vasculature, modulated Akt phosphorylation may cause impaired vasorelaxation via decreased eNOS activation. Diet-induced insulin resistance enhances endothelin-1(ET-1)-mediated vasoc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741337/ https://ncbi.nlm.nih.gov/pubmed/18516099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/Y08-034 |
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