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Multifaceted role of EZH2 in breast and prostate tumorigenesis: Epigenetics and beyond

Overexpression of EZH2 and other PRC2 subunits, such as SUZ12, is associated with tumor progression and poor prognosis in several human malignancies. Nevertheless, the underlying mechanisms driving aberrant EZH2 expression are poorly understood. This review provides molecular insights into the essen...

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Autori principali: Deb, Gauri, Thakur, Vijay S., Gupta, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741216/
https://ncbi.nlm.nih.gov/pubmed/23644490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24532
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